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Researchers like these also tend to express through their research the theory that GHRP-2 may act primarily on nonparenchymal immune cells (such as Kupffer or Kupffer-like macrophages) rather than directly on hepatocytes

Alternatively, MDA metabolism occurs via GSH-mediated pathways, where phosphoglucose isomerase uses GSH as a cofactor to convert MDA to methylglyoxal (MG) in the cytoplasm

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During collagen production, these enzymes require iron in its reduced, ferrous (Fe2+) state to function