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In animal experiments, particularly in mouse models, GDF-15 enhances satiety and reduces food intake through its action on the central nervous system

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Negative allosteric modulation of the glucagon receptor by RAMP2

npj Metab Health Dis 2 , 31 (2024)

However, no significant changes were observed in the domain of learning efficiency, implying that hemodialysis may primarily benefit the amelioration of early changes in thought processing rather than memory improvement