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Transgenic (Tg) mice that overexpress IGF-I in the brain exhibit postnatal brain overgrowth without anatomic abnormality (up to 85%) via an increase in cell number[83] and myelination[84]

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Then, we used the AMPK inhibitor compound C (CC) and found that the therapeutic effect of TP-10@CaP-CTP on cardiac hypertrophy was blocked by CC, as indicated by the CM cell surface area (Fig

The answer depends on several factors including peptide type, molecular modifications (such as PEGylation), dosing frequency, and delivery route

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