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This activation induces the regulation of serine/threonine-specific kinase cascades, followed by insulin receptor substrate (IRS) phosphorylation, enhancing insulin sensitivity

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The highest concentration of carnitine in the human body is found in the epididymis, where its concentration is 2000 times higher than in blood

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However, whilst it is accepted that gains in male fertility are likely to be seen with improvement in total motile count, particularly when at the lower end of the range (Hamilton et al