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The percentage of adults in 2020 with SMI in the past year who had a perceived unmet need for mental health services was highest among young adults aged 18 to 25 (63.4 percent or 2.1 million people), followed by adults aged 26 to 49 (48.0 percent or 3.3 million people), then by adults aged 50 or older (41.4 percent or 1.6 million people) (Figure 53)

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3 Results 3.1 Fluoxetine pretreatment increases adolescent quinpirole-induced locomotion via 5-HT 1A receptors As shown in Figure 1 fluoxetine pretreatment of adolescents, but not adults, increased quinpirole-induced locomotor activity via a 5-HT 1A R mechanism

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These endpoints included global transcriptional regulation, biological pathway activity, ciliary beat frequency, regulation of stress-responsive cellular signaling pathways, release of pro-inflammatory cytokines and growth factors, and epithelial barrier function

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