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In the dynamic simulation of CME_a, the conformations where these two residues form hydrogen bonds with the ligand represent more than half of all conformations with hydrogen bonds

Cross reactivity to following analogues have been tested: dityrosine-conjugated BSA, peroxynitrite-treated BSA, tyrosine (Y), chrolotyrosine(ClY), 3-3-dityrosine (DiY), 3-aminotyrosine (NH2Y), 3-nitrotyrosine (NO2Y), phenylalanine (Phe), o-phosphotyrosine, 3,4-dihydroxyphenylacetic acid (DOPA) and 2-hydroxy-4-phenylacetic acid

He has also received support from the Claire O'Neil Essential Tremor Research Fund (Yale University)

Intriguingly, the R groups exhibited a significant elevation in the plasma ATP compared to the HC and R groups ( Figure 6M )

M.FrancisD

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