bacterial and host-derived glutathione are required to activate prfa Allosteric GSH binding primes for DNA binding. (A B) Glutathione Provides a Source of
Glutathione Provides a Source of Cysteine Essential for Intracellular Multiplication of Francisella tularensis PLOS Pathogens Streptococcus pyogenes Hijacks Host Glutathione for Growth and Innate Immune Evasion mBio Multiple regulatory check points control prfA expression and protein Download Scientific Diagram Listeria monocytogenes utilizes glutathione and limited inorganic sulfur compounds as sources of essential cysteine Infection and Immunity Structural insights into glutathione mediated activation of the master regulator PrfA in Listeria monocytogenes Protein & Cell Springer Nature Link Discovery of a glutathione utilization pathway in Francisella that shows functional divergence between environmental and pathogenic species ScienceDirect
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