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STATINS What they do: Crestor and Lipitor lower blood cholesterol by blocking the liver's production of cholesterol

Co-immunoprecipitation of FBXO22-FKBP12, FBXO22-BRD4s or CRBN-BRD4s HEK293T or HEK393T Nluc-3xFlag-FKBP12 cells were seeded in 10 cm dishes (6 10 6 cells/dish) and incubated overnight at 37 o C to attach

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Coating with PEG reduces opsonization by the immune system, allowing the liposome to circulate longer in the bloodstream and increasing its accumulation in tumor tissues through the enhanced permeability and retention effect