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Parkin interacts with Ambra1 to induce mitophagy

Its role as an inhibitor of cellular death was only discovered in 2012 by a research group Columbia University

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Jeong Y-J, Kang M-J, Lee S-J, Kim C-H, Kim J-C, Kim T-H, et al

Sustained catabolism, rapid skeletal muscle loss, and wound-healing demands often justify higher protein targets, particularly in major burns and selected high-risk critically ill populations (2, 3, 51, 56, 67, 124)