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It makes dosing harder to track, blurs the experience, and in some regulated markets pre-mixed products are restricted or effectively prohibited

We keep pushing the bar, said Braver

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Gearing traditional cigarette ads toward teens has been restricted since 1998

With that patented strain, 22nd Century subsequently created a series of very low nicotine content cigarette products called SPECTRUM that were exclusively provided to academic research institutions for use in clinical studies to assess the physiological and psychological effects of nicotine reduction in heavy smokers

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