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Expert Rev Clin Pharmacol 13:885897

It's just one of these things

Beyond its role in serotonin synthesis, tryptophan plays a central role in the kynurenine pathway, a metabolic pathway critical for the production of nicotinamide adenine dinucleotide (NAD+), a molecule essential for ATP generation in cellular metabolism (Savitz, 2020) (Figure 5)

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( t, u ) The level of STAT1, p-STAT1 and IDO1 in hypoxic MCF-7 cells and sorted HyPerRed high cells and HyPerRed low MCF-7 cells were analyzed Western blot