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When levels drop, the body enters a state of oxidative stress

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Cheraghi E, Soleimani Mehranjani M, Shariatzadeh SM, Nasr Esfahani MH, Alani B

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Subsequently, through the action of divalent metal transporter 1 (DMT1), Fe 2+ enters from the endosomes to the labile iron pool (LIP) in the cytoplasm [71]

found that, while oral glutathione supplementation did not induce changes in GSH levels in the plasma and cellular compartments, a significant increase was observed in the plasma protein-bound fraction [56]