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doi: 10.1016/j.bpa.2019.07.016 [DOI] [PubMed] [Google Scholar] 8.Tardiolo G, Bramanti P, Mazzon E

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The respective ligand was modeled into this density using pre-existing monomers in the CCP4 library for 1 , E-64c and E-64d and a custom ligand built using Coots ligand builder for (2 S ,3 S )- t -ES- a9 - b7 (ref

The thinking is that this method provides a head start, saturating the damaged tissue with the regenerative compound before it even has a chance to circulate through the rest of the body