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Antitumor effect of combined NAMPT and CD73 inhibition in an ovarian cancer model

5-Fluorouracil neurotoxicity in a patient with normal dihydropyrimidine dehydrogenase activity

On one hand, its multi-target therapeutic potential lacks validation through large-scale, randomized, double-blind, placebo-controlled clinical trials in humans, which hinders the effective translation of preclinical findings into clinical applications

Through the upregulation of intestinal Nrf2 and HO-1 expression, vinpocetine dramatically reduced oxidative stress damage

Vilar L, Vilar CF, Lyra R, Freitas MDC

Next up -- we need to start testing carnitine in the context of the ketogenic diet