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In an example application as an anti-infective lock solution for intravascular catheters, the GSNO-CD solution exhibits potent antibacterial activities for both planktonic and biofilm bacteria, both intraluminal and extraluminal environments, both prevention and treatment of infections, and against multiple bacterial strains including a multidrug-resistant strain

The development of DM is associated with neuroendocrine disorders, insulin resistance, oxidative stress, chronic inflammation, and disruptions of gut microbiota

The optical density was measured at 450 nm wavelength using a microplate reader

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Drug repositioning for Alzheimers disease

As AIP is a potent competitive PAL inhibitor, the buildup of phenylalanine without increased PAL activity likely explains the observed effects