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TABLE 4 Characteristics of included articles assessing therapeutic options to prevent ferroptosis in AD stratified by mechanisms involved in ferroptosis

Adult male mice were randomly assigned into three main groups (1-3) based on the neurobehavioural models

Commun Biol 8 , 810 (2025)

Strategies aimed to block the ligandreceptor interaction involve receptor neutralising antibodies (Kalebic et al, 1994)

4.2 Microbial translocation The maintenance of intestinal barrier function relies on the equilibrium of gut microbiota, integrity of the mucosa, and normal functioning of the immune system

Heterologous expression and purification The expression of the fusion protein under the control of a tac promoter was performed in a 2xYT-medium (1.6% tryptone, 1% yeast extract, 0.5% NaCl) containing ampicillin (100 g/ml)