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doi: 10.1007/s10103-013-1264-y 204 KimuraMMotekiHOgiharaM

9 The incidence of dementia increases with patient age and duration of Parkinson disease, with 60 percent of patients who have the disease developing dementia within 12 years of diagnosis

Wearables Wearable devices that use actigraphy to assess sleep-wake dynamics have increased in popularity and availability over the past decade

Pediatrics 1994;93(1): 111

Proc Am Assoc Thorac Surg 3:184-185, 2000

19,20,21 Metabolic reprogramming, characterized by a shift from mitochondrial oxidative phosphorylation to glycolysis, increases the production of toxic byproducts and reactive oxygen species (ROS)