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Liao W-C, Wang Y-J, Huang M-C, Tseng G-F (2013) Methylcobalamin Facilitates Collateral Sprouting of Donor Axons and Innervation of Recipient Muscle in End-to-Side Neurorrhaphy in Rats

Another strategy outlined below relies on inhibition of the xCT system, which mediates the entry of cystine that fuels the trans-sulphuration pathway

Effective systemic dose in pigs of 1.1 mg/kg (~75 mg in humans) showed no adverse effects, representing approximately 300-fold below toxic dose

While these compounds show promise in longevity research, they have important health risks

Tables 1, 2 summarize the inducers and inhibitors of ferroptosis