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Taking advantage of distinct electrophoretic mobilities of wild-type and mutant SOD1 proteins (G85R and L126Z), furthermore, wild-type human SOD1 was found to accumulate as detergent-insoluble aggregates with the mutant proteins in transgenic mice [29, 31, 33, 34], while the interactions in the aggregates would not be simply a co-assembly of mutant and wild-type proteins [33]

The most common side effects are mild injection-site irritation (SubQ), mild nasal stinging or dryness (intranasal), and occasional mild headache during the first few days

Unlike other B12 types, it binds well to blood proteins, allowing it to stay active for several days to weeks after administration