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doi: 10.1007/s11060-022-04090-9

Ethics declarations Ethics approval and consent to participate This study was performed with the approval of the Ethics Committee of Harbin Institute of Technology University and carried out in compliance with the Declaration of Helsinki of the World Medical Association

HMGB1 acts as both a trigger and amplifier of ferroptosis, engaging receptors such as TLR4 and RAGE to propagate inflammation and tissue injury

To provide a more practical perspective, commonly used PDEV cargo-loading strategies and their reported performance characteristics are summarized in Table 4

Crucially, HBV independently suppresses DNA repair capacity by downregulating poly(ADP-ribose) polymerase 1 (PARP1) via YTHDF2-mediated m6A methylationwithout enhancing ROS production or altering oxidative stress pathways [389, 391]

Another study showed that nine out of twelve herbs treated with plasma had higher antioxidant capacity