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Not surprisingly, nicotine acts in the body wherever nicotinic receptors are found, such as on the heart, blood vessels, and muscles

We systematically tested for the effect of bias covariates using metaregression, selected significant bias covariates using the Lasso approach 194,195 and adjusted for the selected bias covariates in the final risk curve

As e-cigarettes, heated tobacco products, and nicotine pouches continue to gain market share in Switzerland, this development underscores the importance of a regulatory framework based on independent, transparent, and regularly updated toxicological assessments

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Nolen-Hoeksema, S., & Watkins, E