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importantly, cumulative exposure (measured in pack-years) was strongly associated with fibrosis severity, with each additional pack-year tripling the likelihood of advanced fibrosis (adjusted OR per pack-year: 3.2

- On initial use, the risk of addiction to nicotine is greater than that of cocaine or alcohol

Dalla Vecchia, L

The WHO said smoking is one of the biggest contributors to a worldwide epidemic of non-communicable, or chronic, diseases such as heart attack, stroke, cancer and emphysema, which accounts for 63 percent of all deaths worldwide, nearly 80 percent of which occur in poorer countries

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Over the 20th century, Dunhill introduced many innovations to the lighter industry