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Mainly localized in the extremities of long bones, OS is characterized by osteolytic lesions associated with ectopic bone formation and the development of pulmonary metastases, which worsen the prognosis [1]

Theriogenology 118:8089

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[6] [7] One large retrospective cohort study has reported that in patients with the presence of an allergic reaction after exposure to a sulfonamide antibiotic, 9.9% had an allergic reaction after receiving a non-antibiotic sulfonamide derivative, while in patients who lacked an allergic reaction after sulfonamide antibiotic exposure, 1.6% had an allergic reaction after administration of a non-antibiotic sulfonamide derivative (adjusted odds ratio 2.8

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