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Most users find that a refill lasts around one day of regular use

Sweets: This variety doubles down on the natural sweetness of the pipe tobacco, often enhanced with subtle, confectionery-like notes

The lack of NRT efficacy, noted in pregnancy compared with non-pregnancy NRT efficacy, could possibly be explained by the increased metabolism of nicotine in pregnancy and the low adherence 1,29

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These findings highlight the need for comprehensive strategies when implementing such bans, considering not only the public health benefits but also the potential economic impacts and the need for effective enforcement to mitigate unintended consequences, like increased illicit trade