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Smoking and dementia risk Alzheimer's Research UK When nicotine from a cigarette reaches your brain, it releases dopamine, the chemical that makes you feel good for a short time. This is what starts the addiction., Nicotine also changes other brain What nicotine does to your brain Smoking doubles your risk of stroke Back of pack A Small Part of the Brain, and Its Profound Effects Cigarette smoking and thinning of the brain's cortex PMC
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