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Neuroprotection diminishes the neural abrasion that chronic stress inflicts, so the brains regulation of the reproductive axis grows more robust

Microinjection of drug compounds into the organoid lumen may provide one approach to access the apical compartment, but this method requires technical expertise and is labor-intensive

In addition, LA protected cortical neurons against A peptide- and hydrogen peroxide-induced damage, suggesting that the neuroprotective effects were partly related to PKB/Akt signaling pathway stimulation (Zhang et al., 2001)

In addition, inflammation induces cyclo-oxygenase-2 (COX-2) expression, thus enhancing prostaglandin (PGE) synthesis [7]

doi: 10.1186/1749-7922-6-5 13

Here, point mutations were introduced within key consensus motifs within the APP tail (previously described in Janurio et al, 2022) and their binding was validated by immunoblotting