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DOX has been found to induce the production of reactive oxygen species, thereby synergistically upregulating the expression of MDR1 and BRCP in conjunction with the high activity of HIF-1 under hypoxia

Multiple-channel automatic pipettes also facilitate the transfer of liquid aliquots between plates

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However, it has been noted that when less specific definitions are used, as may be applied in clinical practice, the ratio of patients is instead majority female (61)