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Protein crystal structures were obtained from the RCSB protein databank (rcsb.org) for ACLY (PDB ID 6POF), ACC (PDB ID 5CSK) and FAS (PDB ID 2VZ8) or UniProt (uniprot.org) for CIC (P53007)

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This is because a butterfly needle's bilateral wings and short length allow a phlebotomist to grip close to the needle and precisely place it in the vein

Rather than being associated with a single mechanism, the peptide appears to interact with multiple signaling pathways that influence how tissues respond to stress and structural disruption