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These vitamins are necessary for the synthesis of DNA, which is required for red blood cell formation

Vitamin B12deficiency can manifest itself in the following clinical pictures: Hyperchromic macrocytic megaloblastic anemia (pernicious anemia, Biermer's anemia, Addison's anemia these are red blood cell maturation disorders) Funicular spinal disease [spinal cord damage] A vitamin B12deficiency confirmed by laboratory diagnostics can occur with: Years of malnutrition and malnutrition (e.g strictly vegetarian diet)

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This aligns with previous plasma metabolomics profiles observed in GWS, where dysregulation of energy metabolism was evident

Improved Insulin Sensitivity Insulin resistance is a precursor to type 2 diabetes and a major driver of chronic inflammation and weight gain

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