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10.1093/rheumatology/27.1.77 229

The second interesting figure to observe here is how many more adducts the female KO mice had then the males

Concurrently, utilizing targeted metabolomics technology, we discovered that AICAR effectively restores the levels of multiple metabolites associated with glycolysis, the TCA cycle, the urea cycle, and tryptophan metabolism and alleviates lipid deposition in IRI-AKI

10.1002/mnfr.202200275 169 WangX.ZhangM.MaoC.ZhangC.MaW.TangJ.et al (2023d)

S-lactoylglutathione activates potassium efflux pumps that acidify the cytoplasm and confer protection against MG

The MELK inhibitor OTSSP167 protects intestinal epithelial cells by maintaining a normal composition of gut microbiota and balancing gut microbiota distribution, inhibiting ferroptosis, reducing the expression of pro-inflammatory factors in intestinal tissues, and suppressing the AKT/IKK/P65 and ERK/IKK/P65 signaling cascades in vitro and in vivo, thereby exerting a protective effect on the intestinal tissues of colitis mice [291, 292]