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Figure 9 In summary, through their customizable design, COF platforms not only overcome key limitations of conventional sensitizers-such as insufficient ROS generation, limited tissue penetration, and poor targeting-but also advance therapeutic paradigms from simple cell ablation to precisely inducing layered, immunogenic forms of cell death

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The potentially beneficial features of IgE include its affinity for the FcR, expressed by the immune effectors responsible for ADCC and ADCP, and the low levels of normal IgE in the blood, which avoids competition with the therapeutic IgE

plasmid #136466, Watertown, MA, United States) plasmids were performed with the transfection reagent FuGENE HD (Promega, Ref: E2311, Promega GmbH, Walldorf, Germany) at a 2:1 FuGENE HD:DNA ratio according to the manufacturer protocol

J Am Chem Soc (2022) 144:347786

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