Mal-Propionyl-Beta-Ala-Val-Cit-PAB(m-PEG8)-MMAE Size:1mg Product Name 6-FAM ethylenediamine Synonyms

Product Name 6-FAM ethylenediamine Synonyms CAS Number N/A Related CAS Molecular Formula C23H18N2O6 Molecular Weight 418

6-SiR-CA CAS Number Related CAS Molecular Formula C37H48ClN3O5Si Molecular Weight 678

877 SMILES CC(C)(C)OC(=O)CN1CCN(CC(=O)NCCCCC(O)=O)CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

dCeMM1 is a glue degrader of RBM39 that functions by re-directing the activity of the CRL4DCAF15 ligase

794 Purity (HPLC) >= 95% Solubility DMSO

Mal-Propionyl-Beta-Ala-Val-Cit-PAB(m-PEG8)-MMAE Size:1mg Product Name 6-FAM ethylenediamine SynonymsSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate