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As well, some people may have allergies or medical conditions that do not allow them to be a good candidate to receive vitamin B12 shots, such as kidney problems, low potassium levels, deficiencies in other vitamins such as iron or folic acid, or just an allergy or sensitivity to vitamin B12 itself

The information provided here is not a substitute for professional medical advice, diagnosis, or treatment

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In mitochondria [edit] The metabolism of propionyl-CoA occurs in the mitochondria and requires Vitamin B 12 (as adenosylcobalamin) to make succinyl-CoA

Each format offers different tradeoffs

Choline is the major precursor of betaine, and it is used by the kidneys to maintain water balance and by the liver as a source of methyl-groups for methionine formation