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However, GC B cells can also differentiate into MBCs that circulate until antigen re-exposure leads to their re-entry into the GC, followed by new rounds of affinity maturation [52, 53]

Analysis was performed using the LC-20 Prominence HPLC system (Shimadzu, Kyoto, Japan) coupled to a LTQ Orbitrap XL Hybrid Ion Trap-Orbitrap Mass Spectrometer (Thermo Fisher Scientific) according to 1 ) with a mixture of water and acetonitrile, both containing 0.1% formic acid

[Abstract] Int Immunopharmacol

Peptide Reconstitution Peptides are stored in a lyophilized (a freeze dried fine powder) state and so need reconstitution before they can be used

Researchers get impatient and shake the vial to dissolve the powder

This gentle approach protects the delicate hormone structure