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This background pain may appear in up to 24%49% of patients, and may be described as burning, stinging, or pulsatile.22,23 The most recent data do not fully support the theory that continuous pain is the result of longstanding paroxysmal TN.23 While the underlying pathophysiological mechanism is not fully understood, it is believed to involve central sensitisation and damage to C fibres of the nerve root

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The complete process maintains sterile conditions because it operates in environments which meet Good Manufacturing Practice (GMP) standards

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AOD-9604's lipolytic activity is suppressed by insulin, so fasted administration is essential