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Experimental studies indicate that E2 enhances the expression and activity of several ETC complexes, including Complex I (NDUFB8), Complex IV (MTCO1) and Complex V (121)

The BMD of the spine, the proximal part of the femur, and the total body were measured with dual-energy x-ray absorptiometry in 136 postmenopausal white women who were scheduled to undergo spine fixation and decompression surgery for degenerative spine disease