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J Refract Surg 24(9):923-7, 2008

[38] found that in both PASMC and PAH rats, HIF-1 regulated mitochondrial dynamics during hypoxia-induced pulmonary vasculature remodeling by directly lowering Drp1 expression and increasing the expression of Mfn2 (Figure 1)

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DESeq2 R package was employed for differential expression analysis between groups, adjusting p -values with Benjamini and Hochberg's method to manage the false discovery rate