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J Androl 2001;22:7378 Wong WY, Thomas CM, Merkus HM, Zielhuis GA, Doesburg WH, Steegers-Theunissen RP: Cigarette smoking and the risk of male factor subfertility: Minor association between cotinine in seminal plasma and semen morphology

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The recovery of regulatory T cell function by the administration of low-dose IL-2, which is an important regulator of Tregs, is another promising therapeutic agent in SLE (85)

In parallel, defective autophagic clearance and ubiquitin-proteasome system dysfunction result in the accumulation of toxic protein species and damaged organelles, perpetuating cellular toxicity [5052]

Abe T, Unno M, Takeuchi H, Kakita T, Katayose Y, Rikiyama T, et al

MTF1 eliminates intracellular iron overload by regulating FPN, thereby protecting intervertebral disc cells from ferroptosis ( Figure 5 ) (179)