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J.BerendseH

10.1016/j.nbd.2016.08.007 341 SmithE

Numbness or tingling sensations Pain in the hands and feet Weakness or fatigue Risk Factors for Developing B12 Deficiency Neuropathy Some people are more likely to get nerve damage from B12 shortage

S - (1,2-Dichlorovinyl)-L-cysteine sulfoxide also caused apoptosis

Therefore, targeting different tumor antigens to overcome antigen heterogeneity and increase the CAR-T cell persistence and efficacy using the genetic modifications in CAR structure and combinatorial treatment strategies can help overcome TME hurdles [8, 9]