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78 Inhibition of ferroptosis can also result from low glucose availability in the TME, which triggers AMP-activated protein kinase (AMPK)-mediated phosphorylation of acetyl-CoA carboxylases and inhibits production of fatty acids, including PUFAs that are necessary for ferroptosis

The increased B cell differentiation into plasma cells allows for autoantibody production leading to immune complex deposition in tissues causing inflammation and tissue injury (140)

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doi: 10.1007/s12035-016-0369-2 54 ChenZJiangRChenMZhengJChenMBraidyNet al

Theoretical Concerns The promotion of angiogenesis by both peptides raises theoretical questions about cancer risk

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