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C: Group 3 retrograde nerve reinnervation with S-100 staining, showing evidence of the epineurium, perineurium, and endoneurium

No established upper limit exists because excess b12 excretes through kidneys without causing harm

Taken together, these results suggest that Ssu72 induces adipogenesis and lipogenesis in white adipocytes by GSK3/-catenin axis under HFD conditions, contributing to adipose tissue expansion during diet-induced obesity

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Furthermore, HFD-induced microbiota dysbiosis disrupted the intestinal barrier, increasing gut pathogenic bacteria and circulating endotoxin, which disequilibrated the local microenvironment and caused inflammation in the lung (Chakradhar, 2017)

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