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It may be one of the substances that will allow for longer periods without B12, which could account for this

doi: 10.1155/2022/9764940

The endocannabinoids produced from arachidonic acid (AA) include anandamide and 2-arachidonoylglycerol, whereas those from omega-3 PUFAs include docosahexaenoyl ethanolamide (from DHA) and oleylethanolamide and palmitoylethanolamide (from EPA) (78)

Annu Rev Biochem 87:10151027 Corina A, Rangel-Ziga OA, Jimnez-Lucena R, Alcal-Daz JF, Quintana-Navarro G, Yubero-Serrano EM, Lpez-Moreno J, Delgado-Lista J, Tinahones F, Ordovs JM (2019) Low intake of vitamin E accelerates cellular aging in patients with established cardiovascular disease: the CORDIOPREV study

Cytokine Networks in Glioma

Following compression injury, however, microglial processes often extend through the glial limitans into the injured meningeal space (white arrows) as evidenced by the presence of microglial processes adjacent to the skull bone (blue)