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16S rRNA profiling revealed enrichment of SCFA-producing genera Bifidobacterium and Prevotella , supporting microbiota-mediated MGBA modulation (Zhu R

Bolsters antioxidant action*

Stressed and injured NASH hepatocytes express and secrete a second Hedgehog ligand, Sonic Hedgehog (SHH), which is positively correlated with hepatocyte ballooning, steatosis, pericellular fibrosis, and fibrosis stage in liver samples from NASH patients (206, 207)

4 However, fentanyl may not be the most appropriate agent due to its very high potency and other clinical scenarios (e.g., acute pain, outpatient management, and the need for oral administration)