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Antioxidant-rich natural compounds, including vitamins, have been found to inhibit ferroptosis and exert cardioprotective effects (201)

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Relative to the conversion in human plasma, the percent conversion values of 7-HMG to unknown-1 in mouse, rat, dog, and monkey plasma were 3.7 0.0, 4.4 0.3, 3.2 0.0, and 8 0.0% (mean SD), respectively