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The spatial arrangement of hepatocytes along the flow from the portal tract of the central vein ensures that bilirubin metabolism further emphasizes the intercellular transfer of bilirubin and its metabolites, maintaining overall homeostasis [28]

doi: 10.1093/jn/nxz029 159 PilankarASinghaviHRaghuramGVSiddiquiSKhareNKJadhavVet al

Hexokinase 2 (HK2), which catalyzes the first step of glycolysis, is stabilized by the deubiquitinase CSN5 in HCC, promoting metastasis

By reducing these oxidative species, they indirectly regulate S-glutathionylation by preventing excessive oxidative stress, which is a trigger for S-glutathionylation

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Phototoxic reactions are characterised by a rapid onset , typically developing within minutes to a few hours following sun exposure