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In hyperuricemia models, this process activates the innate immune system, resulting in elevated serum levels of LPS and pro-inflammatory cytokines like tumor necrosis factor-alpha (TNF-) (Xu D

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4 Cutaneous lesions exhibit erythema, variable degrees of alopecia, scaling, crusting, and lichenification, which are commonly symmetric and most often affect the head (periocular, perioral, and pinnae

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