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Safety data from trials In a paper summarizing 6 randomized, double-blind, placebo-controlled human trials, AOD 9604 did not significantly affect IGF-1 levels, did not impair glucose tolerance, and no serious adverse events (SAEs) were attributed to AOD 9604

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This result further supports the view that the decrease in GSSG content is primarily due to the decrease in total GSH content resulting from the absence of the mutant and not to its recovery

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