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S2CID 9209528

Mitochondrial electron transport chain: Oxidative phosphorylation, oxidant production, and methods of measurement

J Am Soc Nephrol 20:22962304

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Liyanage-Don N, Fung D, Phillips E, Kronish IM

Third, with bifunctional alkylating agents such as nitrogen mustards, the second 2-chloroethyl side chain can undergo a similar cyclization reaction and alkylate a second guanine residue or another nucleophilic moiety, resulting in the crosslinking of two nucleic acid chains or the linking of a nucleic acid to a protein, alterations that would cause a major disruption in nucleic acid function