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As an example, paliperidone has a half-life of about 24 hours 15 and can be administered in a once-daily dosing schedule

Rad AN, Grillari J (2024) Current senolytics: mode of action, efficacy and limitations, and their future

And I, I mean this is, as we know, this is just one of the many bio biohackers or it's a buzzword that everybody that that's putting out there

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It was reported that DRAM1 aggravates the intestinal epithelium damage of IBD patients and mouse models through increasing the activation of JNK/c-Jun pathway, but the expression of DRAM1 shows no significant change in the intestinal tissues with acute inflammation (Zhang et al., 2021)

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