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PMC, 2011

173 Hence, those who poorly metabolize PPIs are likely to exhibit increased suppression of acid production and thus more interference with absorption of vitamin B 12

However, an increase in mutation frequency above a critical threshold (usually 60%80%) leads to pathogenicity and mitochondrial disease manifestations ( 3.2 Oxidative stress Although many chronic diseases are multifactorial in origin, they all are associated with a common process, namely oxidative stress

For the effective treatment of skin cancer, Lamch et al